Cocktail of viruses will help safely cure food poisoning
Traditionally, in acute food poisoning, doctors use antibiotics, which create the effect of carpet bombing on a complex intestinal ecosystem. Scientists from the University of Copenhagen decided to stop this practice and create a means of pinpointing microorganisms that provoke poisoning of people.
As the main enemy is taken the famous E.Coli , it is also an E. coli. The idea is to single out several species of bacteriophages that see it as their prey, and will hunt only for this bacterium, ignoring others. Then, instead of the scorched earth tactics in the intestines, a special operation will be launched to eliminate a particular enemy.
The most difficult thing in this idea was to create a test site. All existing models and systems are oriented only to biochemical and biophysical processes, and Danish scientists were interested in the survival of neutral microbes in the conduct of “hostilities.” Therefore, they designed their own TSI test setup, which not only imitates conditions in the human small intestine, but was also populated with the necessary flora, which has successfully taken root there.
Experiments with promising phages made it possible to distinguish three species that successfully completed the task: they killed almost all of the E. coli and did not touch the other bacteria. Now the authors of the method want to conduct experiments already on living beings, first the mouse, and then people. If they are successful, then in the arsenal of doctors there will be new, sparing means for treating a lot of common diseases.